Peripheral neuropathy
Peripheral neuropathy is a disorder involving the peripheral nervous system (PNS). The central nervous system (CNS) includes your brain and spinal cord, and the PNS includes all of the nerves that come from your spinal cord and innervate the rest of your body. Peripheral neuropathy can be caused by many conditions including vitamin deficiencies, alcoholism, autoimmune diseases, certain medications, unknown causes, and diabetes. When your peripheral nerves become damaged, they do not function properly and can eventually produce symptoms such as pain, tingling, or numbness.
Pharmacologic Therapy
Membrane-stabilizing medications are typically the drug of choice used to treat painful neuropathies. These medications typically calm down irritated nerves,but can have a high rate of side effects that may limit their use. Some of the medications that are particularly effective at treating nerve pain include Cymbalta, Elavil, Lyrica, Tramadol, and Neurontin. These medications may relieve pain but do not help to prevent the progression of the disease.
Pain relievers, such as NSAIDs and opiates, may offer some pain relief, but there is a concern of overuse and dependence that may develop along with other side effects. Opioids are usually not the drug of choice when treating nerve pain.
Advanced Interventional Therapies
Louisiana Pain Specialists has successfully treated patients with painful peripheral neuropathy with a modality called spinal cord stimulation (SCS). Spinal cord stimulation is often thought of as a pacemaker for pain management and can be a very effective long-term treatment modality for neuropathies and other difficult-to-treat pain syndromes.